Harold Lewis is Emeritus Professor of Physics at the University of California, Santa Barbara. Here is his letter of resignation to Curtis G. Callan Jr, Princeton University, President of the American Physical Society.
Anthony Watts describes it thus:
This is an important moment in science history. I would describe it as a letter on the scale of Martin Luther, nailing his 95 theses to the Wittenburg church door. It is worthy of repeating this letter in entirety on every blog that discusses science.